Comparative Genomics and Evolutionary Modularity of Prokaryotes.
Identifieur interne : 000791 ( Main/Exploration ); précédent : 000790; suivant : 000792Comparative Genomics and Evolutionary Modularity of Prokaryotes.
Auteurs : Cedoljub Bundalovic-Torma [Canada] ; John Parkinson [Canada]Source :
- Advances in experimental medicine and biology [ 0065-2598 ] ; 2015.
English descriptors
- KwdEn :
- MESH :
- genetics : Bacteria.
- Biological Evolution, Genomics, High-Throughput Screening Assays.
Abstract
The soaring number of high-quality genomic sequences has ushered in the era of post-genomic research where our understanding of organisms has dramatically shifted towards defining the function of genes within their larger biological contexts. As a result, novel high-throughput experimental technologies are being increasingly employed to uncover physical and functional associations of genes and proteins in complex biological processes. Through the construction and analysis of physical, genetic and metabolic networks generated for the model organisms, such as Escherichia coli, organizational principles of the genome have been deduced, such as modularity, which has important implications toward understanding prokaryotic evolution and adaptation to novel lifestyles.
DOI: 10.1007/978-3-319-23603-2_4
PubMed: 26621462
Affiliations:
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Le document en format XML
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As a result, novel high-throughput experimental technologies are being increasingly employed to uncover physical and functional associations of genes and proteins in complex biological processes. Through the construction and analysis of physical, genetic and metabolic networks generated for the model organisms, such as Escherichia coli, organizational principles of the genome have been deduced, such as modularity, which has important implications toward understanding prokaryotic evolution and adaptation to novel lifestyles.</div></front></TEI><affiliations><list><country><li>Canada</li></country></list><tree><country name="Canada"><noRegion><name sortKey="Bundalovic Torma, Cedoljub" sort="Bundalovic Torma, Cedoljub" uniqKey="Bundalovic Torma C" first="Cedoljub" last="Bundalovic-Torma">Cedoljub Bundalovic-Torma</name></noRegion><name sortKey="Parkinson, John" sort="Parkinson, John" uniqKey="Parkinson J" first="John" last="Parkinson">John Parkinson</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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